2. Weight Gain and Psychological Recovery in Patients with Atypical Anorexia Nervosa: Findings from the Study of Refeeding to Optimize iNpatient Gains (StRONG)

Patients with Atypical Anorexia Nervosa (AAN) have all the features of (AN) but are normal or above weight. Limited data on course and outcome exist in AAN. Purpose: To compare weight gain psychological recovery patients AAN AN. This is a secondary analysis from Study Refeeding to Optimize Inpatient Gains (StRONG) trial, multicenter randomized controlled trial comparing higher-calorie refeeding (HCR) versus lower-calorie (LCR) 120 adolescent young adults hospitalized medical instability AN Weight history was collected upon enrollment. Weight, vital signs, Eating Disorder Examination Questionnaire (EDE-Q) were obtained at admission 1, 3, 6, 12m after discharge. The primary for this definition clinical remission developed AN: restoration ≥95% median BMI (mBMI) plus global EDE-Q score within 1 SD community norms. compared admission, 6 by independent t-tests continuous Fisher’s exact categorical data. Of 111 participants who completed treatment protocol, 48 (43.2%) had 63 (56.8%) Historical %mBMI (prior illness) higher than (129 ± 29 vs. 105 16%, p<.001) as (AAN 95.4 9.1 76.9 5.6 %mBMI, p<.001); 44% those exceeded 95%mBMI admission. regained during follow-up lower 6m (9.5 13.6 9.0, p=0.03) (8.2 11.9 12.7, p=0.03). more likely meet exceed (81 39 40 49% , p<0.001) 12 m 43 mo, p<0.001). Compared AN, mean (3.8 1.7 3.1 1.7, p = .03), did not differ (1.42 1.3 2.2 p=0.16) (1.9 1.6 2.7 1.5, p=.04). proportion scores below norm (10/48, 20.8 25/63, 39.7%, .005 25/48, 52.1% 27/63, 42.9%, p=.3) 52 25/33, p=.5). Over one year follow-up, remained their pre-illness however they threshold just cognitive remission. These findings underscore challenges applying criteria Studies needed develop new metrics